From New York City/Providence RI

Follow 95 N to Providence RI, take I-195 to the Cape & Islands til the end, it will turn into RT 25 (DO NOT TAKE RT6 BEFORE THE BRIDGE-YOU WILL GET LOST!) to the Bourne bridge. Go over the Bourne bridge and there will be a rotary (circle/roundabout) take the 3rd exit (to RT 6) follow road all the way down until you come to a traffic light, take a right and that will bring you onto the onramp for RT 6 East.

From Boston

Take I-93S (Southeast expressway) to RT 3. Follow signs to Cape Cod & Islands. Go over Sagamore Bridge and keep heading on RT 6.

From RT 6

Follow RT 6 past exit 12. You will come to a rotary (circle/roundabout) take the 2nd exit (RT 6) and head towards Eastham and Provincetown. There will be 3 traffic lights (not blinking lights). At the 3rd traffic light there will be a town center, Ben & Jerry's Ice Cream is on the right heading towards Provincetown. We are just beyond the light approximately 1/4 mile on the left, across from St. Aubin's Nursery on the corner of Bayside Drive & Route 6. There will be a large hedge in front and the inn sits back from there. There will be a Burgundy & gold sign with "The Penny House Inn". From the rotary in Orleans we are 5 miles exactly.
Not Driving? You can Fly US Airways (Colgan Air) with direct flights from New York to Hyannis.

You can take a bus with Plymouth and Brockton (Logan Airport) or Bonanza Bus (NY city or Providence RI)

or you can take a ferry to Provincetown (Bay State Ferry) from Boston.